Topic: Hypothalamic Inflammation Improves Though Bariatric Surgery, and Hypothalamic Volume Predicts Short- Term Weight Loss Response in Adults with or without Type 2 Diabetes
Objective(s):
Preclinical research implicates hypothalamic inflammation in obesity and type 2 diabetes pathophysiology. However, their pathophysiological relevance and potential reversibility need to be better defined. We sought to evaluate the effect of bariatric surgery on on radiological biomarkers of HI and the association between the severity of such radiological alterations and post- BS weight loss trajectories. The utility of cerebrospinal fluid large extracellular vesicles enriched for microglial and astrocyte markers in studying HI was also explored.
Speaker: Dr. Sandra Weber
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The University of South Carolina School of Medicine Greenville is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. - 1.00 Attendance